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VOLUME 12 , ISSUE 1 ( January-June, 2021 ) > List of Articles


A View of Adenomatoid Odontogenic Tumor in Ameloblastoma: A Hybrid Variant

Citation Information : A View of Adenomatoid Odontogenic Tumor in Ameloblastoma: A Hybrid Variant. J Health Sci Res 2021; 12 (1):21-25.

DOI: 10.5005/jp-journals-10042-1100

License: CC BY-NC 4.0

Published Online: 21-07-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Aim: Odontogenic tumors (OTs) are a group of lesions encountered in the jaw with diverse histologic patterns. Few cases of hybrid OT have been reported in the literature, and the current knowledge in this entity is limited principally due to its sporadic occurrence and diverse complex histologic picture. Background: Few cases of hybrid presentation of other OT with ameloblastoma are reported previously. This is most often a dilemma to the clinicians and pathologists. This may delay the proper treatment strategy in patients, leading to comorbidities. Ameloblastoma is a benign OT characterized by local aggressiveness, unlimited growth potential, malignant transformation, and metastasis. Case description: This paper reports a case of a hybrid variant of ameloblastoma with adenomatoid odontogenic tumor (AOT) seen in the maxillary region with calcifications and a history of three times recurrence. AOT is believed to be hamartomatous in origin derived from odontogenic epithelium of dental lamina or its remnants. To date, very few cases of this entity have been reported, and it is considered to be either true hybrids or an anomalous histodifferentiation or morphodifferentiation in origin. It is demonstrated with combination of either typical or atypical AOT with ameloblastoma. This type of lesion needs adequate treatment and follow-up modalities. Conclusion: Hybrid entities are very rare tumors comprising two different tumors each of which conforms to an exactly defined tumor category. Therefore, the identification and treatment of such an entity are extremely important. Clinical significance: Cases with long-term history and recurrences should be evaluated with proper clinical and histological examination.

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