Journal of Health Sciences & Research

Register      Login

VOLUME 12 , ISSUE 2 ( July-December, 2021 ) > List of Articles

Original Article

Knowledge, Attitude, and Practices of Healthcare Workers on the Use of Hydroxychloroquine Prophylaxis against COVID-19 Infection

Shivani Juneja, Simranjot Kaur, Shobha Rana, Ashwani Kumar, Kulvir Singh

Keywords : Coronavirus, Healthcare, Hydroxychloroquine, Prophylaxis

Citation Information : Juneja S, Kaur S, Rana S, Kumar A, Singh K. Knowledge, Attitude, and Practices of Healthcare Workers on the Use of Hydroxychloroquine Prophylaxis against COVID-19 Infection. J Health Sci Res 2021; 12 (2):27-30.

DOI: 10.5005/jp-journals-10042-1107

License: CC BY-NC 4.0

Published Online: 25-03-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Introduction/aim: Coronavirus has created critical situations around the world. It became a global challenge to adopt preventive measures and start a supportive therapy. The use of hydroxychloroquine as prophylaxis was advised by the Indian Council of Medical Research (ICMR). In view of this recommendation, this study was planned to know the perspective of healthcare workers (HCWs) on hydroxychloroquine. The knowledge, attitude, and practice of HCWs on the use of hydroxychloroquine prophylaxis against coronavirus disease-2019 (COVID-19) had been assessed in this study. Materials and methods: A validated e-questionnaire including 20 questions was shared with the HCWs via the identified WhatsApp groups as well as the official mail IDs. Data were collected online through Google forms and analyzed by using descriptive analysis. Results: A total of 76 HCWs participated in this study, whereas 42% of them were working in COVID-19-assigned areas. Twenty-nine (38%) HCWs agreed that the standard precautions could avoid cross-transmission of COVID-19 infection but a few of them consider hydroxychloroquine prophylaxis as a standard precaution. Conclusion: Hydroxychloroquine was advised by ICMR for COVID-19 prophylaxis; however, a small proportion of HCWs considered it as a standard precaution against COVID-19 infection along with washing hands, using a face mask, use of personal protective equipment kit, and social distancing.

  1. World Health Organization. Coronavirus disease-2019 (COVID-19) Situation Report-51. Geneva: WHO. 2020 [Accessed May 10, 2020]. Available from:
  2. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020;382(8):727–733. DOI: 10.1056/NEJMoa2001017.
  3. Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 2020;382:1199–1207. DOI: 10.1056/NEJMoa2001316.
  4. Olum R, Chekwech G, Wekha G, et al. Coronavirus disease-2019: knowledge, attitude, and practices of health care workers at Makerere University Teaching Hospitals, Uganda. Frontiers in Public 2020;8:181. DOI: 10.3389/fpubh.2020.0018.
  5. Reuben RC, Danladi MMA, Saleh DA, et al. Knowledge, attitudes and practices towards COVID-19: an epidemiological survey in North-Central Nigeria. J Community Health 2021;46(3):457–470. DOI: 10.1007/s10900-020-00881-1.
  6. Bhagavathula AS, Aldhaleei WA, Rahmani J, et al. Knowledge and perceptions of COVID-19 among health care workers: cross-sectional study. JMIR Public Health Surveill 2020;6(2):e19160. DOI: 10.2196/19160.
  7. Zhang M, Zhou M, Tang F, et al. Knowledge, attitude, and practice regarding COVID-19 among healthcare workers in Henan, China. J Hosp Infect 2020;105(2):183–187. DOI: 10.1016/j.%20jhin.2020.04.012.
  8. Singh A, Kumar H, Gupta P, et al. Assessment of knowledge, attitude, and practices towards hydroxychloroquine pre-exposure prophylaxis among health care professionals. Indian J Comm Health 2020;32(4):681–687. DOI: 10.47203/IJCH.2020.v32i04.012.
  9. Advisory on the use of Hydroxy-chloroquine as prophylaxis for SARS-CoV-2 infection [Assessed on May 15, 2020]. Available from: chloroquinasprophylaxisforSARSCoV2infection.pdf.
  10. Jindal V, Mittal S, Kaur T, et al. Knowledge, anxiety and the use of hydroxychloroquine prophylaxis among health care students and professionals regarding COVID-19 pandemic. Adv Respir Med 2020;88(6):520–530. DOI: 10.5603/ARM.a2020.0163.
  11. Nagaraja BS, Ramesh KN, Dhar D, et al. HyPE study: hydroxychloroquine prophylaxis-related adverse events’ analysis among healthcare workers during COVID-19 pandemic: a rising public health concern. J Public Health (Oxf) 2020;42(3):493–503. DOI: 10.1093/pubmed/fdaa074.
  12. Chatterjee P, Anand T, Singh KJ, et al. Healthcare workers and SARS-CoV-2 infection in India: a case control investigation in the time of COVID-19. Indian J Med Res 2020;151(5)459–467. DOI: 10.1093/pubmed/fdaa074.
  13. Jain A, Singh A, Verma AK, et al. Assessment of awareness towards pharmacovigilance programme of India and reporting of adverse drug reactions among nurses in a tertiary care hospital. Int J Basic Clin Pharmacol 2018;7:1357–1364. DOI: 10.18203/2319-2003.ijbcp20182682.
  14. Bhattacharya R, Chowdhury S, Nandi A, et al. Pre-exposure hydroxychloroquine prophylaxis for COVID-19 in healthcare workers: a retrospective cohort. Int J Res Med Sci 2021;9:89–96. DOI: 10.18203/2320-6012.ijrms20205444.
  15. Chen J, Liu D, Liu L, et al. A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19. Zhejiang Da Xue Xue Bao Yi Xue Ban 2020;49(2):215–219 [Chinese]. DOI: 10.3785/j.issn.1008-9292.2020.03.03.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.