Neurofibroma (NF) is a benign tumor of nerve tissue origin, derived from the cells that constitute the nerve sheath. Neurofibroma is seen either as solitary lesion or as a part of generalized syndrome neurofibromatosis (Von Recklinghausen disease of the skin). The solitary form does not differ from the disseminated form or the multiple form of the disease except that systemic and hereditary factors present in the disseminated form are absent in the solitary type. We report a case of 60-year-old female who visited the department with a complaint of painless swelling on the dorsal surface at the anterior one-third of tongue since 3 to 4 years. The lesion was excised under local anesthesia. Based on the clinical features, histopathological examination, and immunohistochemical analysis, the diagnosis of plexiform neurofibroma (PN) was given. Isolated PN is a rare tumor. The present case is an isolated PN of the tongue that was not associated with neurofibromatosis. Solitary NFs rarely change into a malignant form. However, Steward and Bailey have drawn attention to the fact that it is important to know whether the tumor is benign or malignant before excision.