Journal of Health Sciences & Research

Register      Login

VOLUME 11 , ISSUE 2 ( July-Dec, 2020 ) > List of Articles

REVIEW ARTICLE

In vitro Evidence of Dose-dependent Decrease of Uropathogenic E. coli after Consuming Commercial Cranberry Capsules in Type 2 Diabetic Premenopausal Adult Women: A Literature Review

Dipika Dabas

Citation Information : Dabas D. In vitro Evidence of Dose-dependent Decrease of Uropathogenic E. coli after Consuming Commercial Cranberry Capsules in Type 2 Diabetic Premenopausal Adult Women: A Literature Review. J Health Sci Res 2020; 11 (2):58-63.

DOI: 10.5005/jp-journals-10042-1094

License: CC BY-NC 4.0

Published Online: 06-04-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

Urinary tract infections (UTIs) arise due to the invasion of pathogenic microorganisms in the urinary tract, resulting in inflammatory reactions in the epithelial linings of the urinary tract. The presence of pathogenic bacteria colonization more than 100,000 microbes of the same strain per milliliter of the urine in two consecutive urine samples is said to be a positive specimen for infection. An electronic search was conducted by using the PubMed database of the library of Unitec Institute of Technology with key research terms “cranberry,” “urinary tract infections,” and “type 2 diabetes.” These specifications resulted in a number of research studies and review articles, but for this literature review, only random controlled trials, comparative studies, pilot studies, and controlled clinical trials were considered. A total of twelve studies were selected for this review, out of which nine were randomized controlled clinical trials, two were co-relational or observational studies, and one was pilot study. The search was not limited to studies on women; rather, an extensive search was carried out in other subpopulations like children, older age-group people, pregnant women, males, and healthy females that were carried out and published between 2008 and 2014. The random controlled trials in the present review provide level 2 evidence, observational studies provide level 4 evidence, and pilot studies provide level 6 evidence. These levels of evidences are mentioned according to the guidelines provided by Polit and Beck.


HTML PDF Share
  1. Shankel S. Symptoms and signs. In Bacterial urinary tract infections. Retrieved from http://www.merckmanuals.com/professional/genitor-urinary-disorders/urinary_tractinfections_uti/bacterial_urinary tract_infections. html # v 10 52 851; 2007.
  2. Nicolle LE, Bradley S, Colgan R, et al. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40(5):643–654. DOI: 10.1086/427507
  3. Polit DF, Beck CT. Nursing research: Generating and assessing evidence for nursing practice (9th ed.). Philadelphia: Lippincott, Williams & Wilkins; 2012.
  4. Patterson JE, Andriole VT. Bacterial urinary tract infections in diabetes. Infect Dis Clin North Am 1997;11(3):735–750. DOI: 10.1016/s0891-5520(05)70383-4.
  5. Joshi N, Caputo GM, Weitekamp MR, et al. Infections in patients with diabetes mellitus. N Engl J Med 1999;341(25):1906–1912. DOI: 10.1056/NEJM199912163412507.
  6. Fünfstück R, Nicolle LE, Hanefeld M, et al. Urinary tract infection in patients with diabetes mellitus. Clin Nephrol 2012;77(1):40–48. DOI: 10.5414/cn107216.
  7. Geerlings SE, Stolk RP, Camps MJ, et al. Asymptomatic bacteriuria can be considered a diabetic complication in women with diabetes mellitus. Adv Exp Med Biol 2000;485:309–314. DOI: 10.1007/0-306-46840-9_41.
  8. Truzzi JC, Almeida FM, Nunes EC, et al. Residual urinary volume and urinary tract infection—when are they linked? J Urol 2008;180(1):182–185. DOI: 10.1016/j.juro.2008.03.044.
  9. Valerius NH, Eff C, Hansen NE, et al. Neutrophil and lymphocyte function in patients with diabetes mellitus. Acta Med Scand 1982;211(6):463–467. DOI: 10.1111/j.0954-6820.1982.tb01983.x.
  10. Hosking DJ, Bennett T, Hampton JR. Diabetic autonomic neuropathy. Diabetes 1978;27(10):1043–1055. DOI: 10.2337/diab.27.10.1043.
  11. Jancel T, Dudas V. Management of uncomplicated urinary tract infections. West J Med 2002;176(1):51–55. DOI: 10.1136/ewjm.176.1.5.
  12. Brown JS, Wessells H, Chancellor MB, et al. Urologic complications of diabetes. Diabetes Care 2005;28(1):177–185. DOI: 10.2337/diacare.28.1.177.
  13. Kofteridis DP, Papadimitraki E, Mantadakis E, et al. Effect of diabetes mellitus on the clinical and microbiological features of hospitalized elderly patients with acute pyelonephritis. J Am Geriatr Soc 2009;57(11):2125–2128. DOI: 10.1111/j.1532-5415.2009.02550.x.
  14. Schappert S, Burt C. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1997. National Centre for Health Statistics. Vital Health Stat 1999;13(143):1–39.
  15. Jepson R, Craig J. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2012;10(10):CD001321. DOI: 10.1002/14651858.CD001321.pub5.
  16. Colgan R, Nicolle LE, McGlone A, et al. Asymptomatic bacteriuria in adults. Am Fam Physician 2006;74(6):985–990.
  17. Delzell JE, Lefevre ML. Urinary tract infections during pregnancy. Am Fam Physician 2000;61(3):713–720.
  18. Gilstrap LC, Leveno KJ, Cunningham FG, et al. Renal infection and pregnancy outcome. Am J Obstet Gynecol 1981;141(6):709–716. DOI: 10.1016/s0002-9378(15)33316-0.
  19. Hirji I, Guo Z, Andersson SW, et al. Incidence of urinary tract infection among patients with Type-2 diabetes in the UK General Practice Research Database (GPRD). J Diabetes Complications 2012;26(6):513–516. DOI: 10.1016/j.jdiacomp.2012.06.008.
  20. Zhanel GG, Nicolle LE, Harding GK. Prevalence of asymptomatic bacteriuria and associated host factors in women with diabetes mellitus. The Manitoba Diabetic Urinary Infection Study Group. Clin Infect Dis 1995;21(2):316–322. DOI: 10.1093/clinids/21.2.316.
  21. Schneeberger C, Kazemier BM, Geerlings SE. Asymptomatic bacteriuria and urinary tract infections in special patient groups: women with diabetes mellitus and pregnant women. Curr Opin Infect Dis 2014;27(1):108–114. DOI: 10.1097/QCO.0000000000000028.
  22. Soo Park B, Lee SJ, Wha Kim Y, et al. Outcome of nephrectomy and kidney-preserving procedures for the treatment of emphysematous pyelonephritis. Scand J Urol Nephrol 2006;40(4):332–338. DOI: 10.1080/00365590600794902.
  23. Freeman JT, Rubin J, McAuliffe GN, et al. Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study. Antimicrob Resist Infect Control 2014;3:27. DOI: 10.1186/2047-2994-3-27.
  24. Williamson DA, Lim A, Thomas MG, et al. Incidence, trends and demographics of Staphylococcus aureus infections in Auckland, New Zealand, 2001–2011. BMC Infect Dis 2013;13:569. DOI: 10.1186/1471-2334-13-569.
  25. Liu Y, Black MA, Caron L, et al. Role of cranberry juice on molecular-surface characteristics and adhesion behavior of Escherichia coli. Biotechnol Bioeng 2006;93(2):297–305. DOI: 10.1002/bit.20675.
  26. McMurdo M, Argo I, Phillips G, et al. Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? A randomized controlled trial in older women. J Antimicrob Chemother 2009;63(2):389–395. DOI: 10.1093/jac/dkn489.
  27. Lee YL, Najm W, Owens J, et al. Antimicrobial activity of urine after ingestion of cranberry: A pilot study. Evid Based Complement Alternat Med 2010 Jun;7(2):227–232. DOI: 10.1093/ecam/nem183.
  28. Monique AAC, Hout WB, Putter H, et al. Effectiveness of cranberry capsules to prevent urinary tract infections in vulnerable older persons: a double-blind randomized placebo-controlled trial in long-term care facilities. J Am Geriatr Soc 2014 Jan;62(1):103–110. DOI: 10.1111/jgs.12593.
  29. Satoshi T, Ryoichi H, Mitsuru Y, et al. A randomized clinical trial to evaluate the preventive effect of cranberry juice (UR65) for patients with recurrent urinary tract infection. J Infect Chemother 2013 Feb;19(1):112–117. DOI: 10.1007/s10156-012-0467-7.
  30. Ferrara P, Romaniello L, Vitelli O, et al. Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand J Urol Nephrol 2009;43(5):369–372. DOI: 10.3109/00365590902936698.
  31. Salo J, Unari M, Helminen M, et al. Cranberry juice for the prevention of recurrences of urinary tract infections in children: a randomized placebo-controlled trial. Clin Infect Dis 2012 Feb;54(3):340–346. DOI: 10.1093/cid/cir801.
  32. Wing D, Rumney P, Preslicka C, et al. Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: A randomized, controlled pilot study. J Urol 2008;180(4):1367–1372. DOI: 10.1016/j.juro.2008.06.016.
  33. Howell AM, Botto H, Combesure C, et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. BMC Infect Dis 2010;10(1):94–104. DOI: 10.1186/1471-2334-10-94.
  34. Burleigh AE, Benck SM, McAchran SE, et al. Consumption of sweetened, dried cranberries may reduce UTI incidence in susceptible women: a modified observational study. Nutr J 2013;12(1):139. DOI: 10.1186/1475-2891-12-139.
  35. Cowan CC, Hutchison C, Cole T, et al. A randomised double-blind placebo-controlled trial to determine the effect of cranberry juice on decreasing the incidence of urinary symptoms and urinary tract infections in patients undergoing radiotherapy for cancer of the bladder or cervix. Clin Oncol (R Coll Radiol) 2012;24(2):e31–38. DOI: 10.1016/j.clon.2011.05.009.
  36. Phillips G, Gerard A, Nicolas B, et al. Cranberry versus placebo in the prevention of urinary infections in multiple sclerosis: a multicenter, randomized, placebo-controlled, double-blind trial. Mult Scler 2014 Aug;20(9):1252–1259. DOI: 10.1177/1352458513517592.
  37. Lavigne JP, Bourg G, Combesaue C, et al. In-vitro and in-vivo dose-dependent decrease of uropathogenic Escherichia coli virulence after consumption of commercial Vaccinum macrocarpon (cranberry) capsules. Clin Microbiol Infect 2008 Apr;14(4):350–355. DOI: 10.1111/j.1469-0691.2007.01917.x.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.