Comparison of Ability of Platelet-rich Fibrin vs CollaPlug in maintaining the Buccal Bone Height of Sockets following Extractions in 20 Patients
Madhumati Singh, G Madhan
Citation Information :
Singh M, Madhan G. Comparison of Ability of Platelet-rich Fibrin vs CollaPlug in maintaining the Buccal Bone Height of Sockets following Extractions in 20 Patients. J Health Sci Res 2017; 8 (1):1-6.
The preservation of bone volume immediately after tooth removal is necessary to optimize the success of implant placement in terms of esthetics and function. The objectives of this study were to compare the ability of Choukroun's platelet-rich fibrin (PRF) versus CollaPlug (Zimmer) in maintaining the buccal bone height of sockets following extractions in patients.
Materials and methods
Twenty patients who required tooth extraction and implant placement were enrolled in this study. The patients were randomly divided into two groups. They are group I PRF group and group II CollaPlug group. The vertical buccal crestal bone heights were measured immediately after extraction and 4 months postextraction and implants were placed.
The buccal crestal bone level in the CollaPlug group had a baseline mean of 4.67 ± 0.54 and a postmean of 6.98 ± 0.60, whereas in the PRF group baseline mean was 5.43 ± 0.47 and postmean was 6.93 ± 0.55. The bone resorption was found in both the groups (2.31 mm for CollaPlug and 1.5 mm for PRF), in agreement with previous studies. However, there was increased bone loss in CollaPlug group compared with PRF group, which was found statistically significant.
In conclusion, within the limits of the present study, the two tested socket preservation materials seem to be effective in the treatment of extraction sockets, even though the design of the study did not allow us to evaluate to what extent the clinical improvement could be attributed to the PRF per se, since a negative control was not included in this investigation. However, preparation of PRF is not very cumbersome and inexpensive, which makes it a better socket preservation material than CollaPlug.
How to cite this article
Madhan G, Singh M. Comparison of Ability of Platelet-rich Fibrin vs CollaPlug in maintaining the Buccal Bone Height of Sockets following Extractions in 20 Patients. J Health Sci Res 2017;8(1):1-6.
Alveolar bone preservation in extraction sockets using non-resorbable dPTFE membranes: a retrospective non-randomized study. J Periodontol 2008 Aug;79(8):1355-1369.
Osseous repair of the postextraction alveolus in man. Oral Surg Oral Med Oral Pathol 1966 Jun;21(6):805-813.
The time sequence of tissue regeneration in human extraction wounds. Oral Surg Oral Med Oral Pathol 1969 Mar;27(3):309-318.
Differentiation of periodontal ligament fibroblasts into osteoblasts during socket healing after tooth extraction in the rat. Anat Rec 1994 Dec;240(4):492-506.
Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog. J Clin Periodontol 2005 Jun;32(6):645-652.
Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Periodontics Restorative Dent 2003 Aug;23(4):313-323.
The osteogenic activity of bone removed from healing extraction sockets in humans. J Periodontol 1982 Feb;53(2):81-85.
Alveolar ridge maintenance with solid nonporous hydroxylapatite root implants. Oral Surg Oral Med Oral Pathol 1984 Nov;58(5):511-521.
Ridge preservation with freeze-dried bone allograft and a collagen membrane compared to extraction alone for implant site development: a clinical and histologic study in humans. J Periodontol 2003 Jul;74(7):990-999.
Extraction site reconstruction for alveolar ridge preservation. Part 2: membrane-assisted surgical technique. J Oral Implantol 2001;27(4):194-197.
Ridge preservation: what is it and when should it be considered. Aust Dent J 2008 Mar;53(1):11-21.
Ridge preservation following tooth extraction using a polylactide and polyglycolide sponge as space filler: a clinical and histological study in humans. Clin Oral Implants Res 2003 Oct;14(5):651-658.
Platelet-rich fibrin: evolution of a second-generation platelet concentrate. Indian J Dent Res 2008 Jan-Mar;19(1):42-46.
Platelet-rich plasma growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998 Jun;85(6):638-646.
Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Mar;101(3):e37-e44.
Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Mar;101(3):e45-e50.
Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leukocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Mar;101(3):e51-e55.
Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Mar;101(3):e56-e60.
Alveolar ridge preservation following extraction of maxillary anterior teeth. Report on 23 consecutive cases. J Periodontol 1996 Apr;67(4):390-395.
Ridge preservation technique for optimal esthetics and function: the Bio-Col technique. Compend Contin Educ Dent 1999;6(Suppl):3-11.
Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents. Proc Natl Acad Sci U S A 1984 Apr;81(8):2396-2400.
Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants 2003 Jan-Feb;18(1):93-103.
Platelet-poor plasma stimulates proliferation but inhibits differentiation of rat osteoblastic cells in vitro. Clin Oral Implants Res 2009 Jun;20(6):616-623.
Platelet-rich fibrin (PRF) is a bioscaffold and reservoir of growth factors for tissue regeneration. Tissue Eng Part A 2011 Feb;17(3-4):349-359.
Clinical and histologic evaluation of bone-replacement grafts in the treatment of localized alveolar ridge defects. Part 1: mineralized freeze-dried bone allografts. Int J Periodontics Restorative Dent 2003 Feb;23(1):29-35.
Cigarette smoking in a periodontal practice. J Periodontol 1992 Feb;63(2):100-106.
The effect of nicotine on incorporation of cancellous bone graft in an animal model. Spine (Phila Pa 1976) 1995 Oct;20(20):2198-2202.
The effect of cigarette smoking on dental implants and related surgery. Implant Dent 2005 Dec;14(4):357-361.
Common implant-related advanced bone grafting complications: classification, etiology, and management. Implant Dent 2008 Dec;17(4):389-401.
Effects of sex hormones on production of interleukin-1 by human peripheral monocytes. J Periodontol 1999 Jul;70(7):757-760.
Tissue integrated prostheses in clinical dentistry. Int Dent J 1985 Dec;35(4):259-265.
Histologic findings after implantation and evaluation of different grafting materials and titanium micro screws into extraction sockets: case reports. J Periodontol 1998 Apr;69(4):414-421.
A novel model system for the study of experimental guided bone formation in humans. Clin Oral Implants Res 1996 Mar;7(1):38-47.
Guided tissue regeneration in jawbone defects prior to implant placement. Clin Oral Implants Res 1994 Jun;5(2):92-97.
Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol 2005 Feb;32(2):212-218.
Ridge preservation with the use of Bio-Oss collagen: A 6-month study in the dog. Clin Oral Implants Res 2009 May;20(5):433-440.
Ridge alterations following tooth extraction with and without flap elevation: an experimental study in the dog. Clin Oral Implants Res 2009 Jun;20(6):545-549.