The study comprised 30 subjects, equally divided into three groups of clinically healthy periodontium, nonsmokers with chronic periodontitis, and smokers with chronic periodontitis. Clinical measurements, saliva, and blood samples were obtained. Biochemical analysis for the estimation of calcium was performed. Blood samples were collected through venipuncture method.

Comparison of mean serum calcium between the three groups by analysis of variance showed highly statistically significant difference (F = 23.92, p = 0.001).

Smokers with periodontitis exhibited reduced levels of calcium as compared with nonsmokers with periodontitis and the differences were statistically significant.

Kasagani SK, Rao A, Rajan S, Fatima G, Tapashetti R. Estimation of Salivary and Serum Calcium Levels in Smokers and Nonsmokers with Chronic Periodontitis. J Health Sci Res 2016;7(2):35-37.

Preemptive analgesia is an evolving concept where therapeutic intervention be made prior to the onset of pain. This study was done to evaluate the effectiveness of diclofenac sodium 100 mg as preemptive analgesic administered 1 hour before removal of impacted third molars using split mouth study model.

A randomized placebo control study was done on 30 patients requiring bilateral impacted tooth removal. Patients were administered 100 mg of diclofenac sodium and placebo 1 hour prior to surgery at different appointments. Patients were assessed for intraoperative pain and postoperative pain with visual analog scale on 1st, 2nd, and 3rd postoperative days.

Statistical difference was found in pain experience during 1st postoperative day (p = 0.0153). Patients after receiving diclofenac sodium 100 mg experienced less pain compared to placebo side. There was no difference found in pain experience between the study and control groups on subsequent postoperative days and overall pain experience.

Better management of pain improves quality of life after procedure. Thus, preemptive analgesia may be beneficial in reducing pain intensity. Larger sample blinded studies may prove efficiency of preemptive analgesia.

Rangaswamy S, Sheshappa KN, Srikanthan R. Preemptive Analgesic Efficacy of Diclofenac Sodium for Surgical Removal of Impacted Third Molars. J Health Sci Res 2016;7(2):38-41.

Aghanashini S, Puvvalla B, Mundinamane DB, Apoorva SM, Bhat D, Lalwani M. A Comprehensive Review on Dental Calculus. J Health Sci Res 2016;7(2):42-50.

Sahu GK, Consul S, Nandakishore KJ, Shubhashini N, Geeta IB, Idris Md. Rotary Endodontics or Reciprocating Endodontics: Which is New and Which is True? J Health Sci Res 2016;7(2):51-57.

Nalini MS, Kumar B, Shroff S. Management of an Infected Maxillary Periapical (Radicular) Cyst through Nasal Antrostomy. J Health Sci Res 2016;7(2):58-62.

Singh N, Anuroopa P, Savita S. Revitalization of periodontally Compromised Tooth using Platelet-rich Fibrin. J Health Sci Res 2016;7(2):63-66.

Kamra S, Pai KM, Chhaparwal Y. Intramuscular Hemangioma: Enigmatic Dilemma in Diagnosis. J Health Sci Res 2016;7(2):67-70.

Guru SR, Singh SS, Guru RC. Peripheral Cemento-ossifying Fibroma: A Report of Two Cases. J Health Sci Res 2016;7(2):71-75.